Our Projects

Specific studies which have been made possible by the existence of the UK and Ireland Juvenile Dermatomyositis Cohort Biomarker Study and Repository, include :

L. Wedderburn
Immunological characterisation of the infiltrate in JDM muscle
L. Wedderburn
Tracking of lymphocyte changes before or after flare of active disease
L. Wedderburn
Analysis of MHC Class 1 expression in an animal model of myositis
L. Wedderburn
Recognition of MHC Class 1 molecules on muscle cells by lymphocytes (CD8 T cells or NK cells)
K. Nistala
The role of muscle ultrasound in juvenile dermatomyositis
L. Wedderburn
Investigation of alterations of MRP8/14 proteins in juvenile dermatomyositis
J. Davidson
Autoantibodies in Juvenile Dermatomyositis, Scleroderma and overlap syndromes
H. Ireland
Do functional gene variants in anti-inflammatory pathways alter the course of disease and allow greater inflammatory response?
P. Brogan
Fetuin-A and calcinosis in Juvenile dermatomyositis
L. Wedderburn
Genotyping analysis in JDM for phenotype: genotype correlation